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VERSION:2.0
PRODID:icalendar-ruby
CALSCALE:GREGORIAN
X-WR-CALNAME:Ph.D. Dissertation Defense: Yu-Jung Lin 
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260609T213302Z
UID:tag:localist.com\,2008:EventInstance_52241993562010
DTSTART:20260413T130000Z
DTEND:20260413T150000Z
DESCRIPTION:Title: Air Pollution Exposure Across Microenvironments and Asso
 ciated Metabolic Pathways in Children Aged 3–4 Years\n\nAbstract: Childr
 en are among the most vulnerable groups to the adverse health effects of a
 ir pollution due to their high breathing rates\, developing immune systems
 \, and time spent outdoors and in multiple microenvironments. Several stud
 ies have shown that exposure to air pollution in early life plays a vital 
 role in triggering adverse health outcomes in adulthood\, such as respirat
 ory and cardiovascular disease. Currently\, only a few studies have focuse
 d on children's exposure to air pollution and related health outcomes\, es
 pecially among toddlers\, due to challenges in conducting research with yo
 ung children\, including compliance with protocols and retention rates. Th
 is dissertation was designed to fill critical data gaps regarding early-li
 fe exposure by assessing indoor\, outdoor\, and personal air pollution (su
 ch as particulate matter\, PM2.5\, black carbon\, BC\, ozone\, O3\, nitrog
 en dioxide NO2 and trace metals\, copper Cu\, zinc Zn\, lead Pb\, cadmium 
 Cd\, chromium Cr\, nickel Ni\, etc.) levels among children aged 3–4 year
 s in Atlanta\, Georgia. This dissertation integrates exposure assessment\,
  correction of low-cost PM sensors\, and metabolomics to examine short-ter
 m air pollution exposure and its metabolic impacts. We collected indoor\, 
 outdoor\, and personal exposure data across seven sampling campaigns at th
 ree daycare centers: high-traffic (S2)\, intermediate (S3)\, and backgroun
 d (S1). Saliva samples were analyzed using LC-MS-based metabolomics\, and 
 mixed-effects models were applied to investigate associations between poll
 utant exposure and metabolic pathways related to oxidative stress\, lipid 
 metabolism\, and inflammation\, while adjusting for sex\, race\, temperatu
 re\, season\, and baseline of metabolites. The results will improve unders
 tanding of mechanistic pathways linking short-term exposure to metabolic p
 erturbations\, guiding interventions to protect children's health.\n\nChai
 r: Dr. Roby Greenwald
GEO:33.752114;-84.385475
LOCATION:Urban Life Building\, 446
SUMMARY:Ph.D. Dissertation Defense: Yu-Jung Lin 
URL;VALUE=URI:https://calendar.gsu.edu/event/phd-dissertation-defense-yu-ju
 ng-lin
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