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VERSION:2.0
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CALSCALE:GREGORIAN
X-WR-CALNAME:Applied and Computational Math Seminar: Optimizing Cell Prolif
 eration in Tissue Engineering: Interplay of Nutrient Dynamics\, Scaffold E
 lasticity\, and Cell Hunger Rate in Scaffold Channels
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260906T211357Z
UID:tag:localist.com\,2008:EventInstance_46013555596818
DTSTART:20240402T170000Z
DTEND:20240402T180000Z
DESCRIPTION:Date and Time: 04/02/2024\, 1 - 2 p.m.\n\nLocation: 25 Park Pla
 ce\, Room 1441\n\nApplied and Computational Math Seminar: Optimizing Cell 
 Proliferation in Tissue Engineering: Interplay of Nutrient Dynamics\, Scaf
 fold Elasticity\, and Cell Hunger Rate in Scaffold Channels\n\nSpeaker: Ha
 niyeh Fattahpour\, Department of Mathematics\, Georgia State University\n\
 nTitle: Optimizing Cell Proliferation in Tissue Engineering: Interplay of 
 Nutrient Dynamics\, Scaffold Elasticity\, and Cell Hunger Rate in Scaffold
  Channels\n\nAbstract: Tissue-engineering scaffolds contain channels lined
  by cells that allow nutrient-rich culture medium to pass through to encou
 rage cell proliferation. Several factors have significant impacts on the t
 issue growth\, including the nutrient flow rate and concentration in the f
 eed\, scaffold elasticity as well as cell properties. Recent studies have 
 investigated these effects separately\; however\, in this work\, we examin
 e all of them simultaneously. Our objectives in this work are as follows: 
 (i) developing a mathematical model describing the nutrient flow dynamics 
 and concentration\, scaffold elasticity and cell proliferation\; (ii) solv
 ing the model and then simulating the cell proliferation process\; (iii) o
 ptimizing the initial configuration of the scaffold channels to maximize t
 he cell growth. The results of our study demonstrate that the rate of nutr
 ient consumption by the cells (cell hunger rate) and the scaffold elastic 
 compliance have an impact on tissue growth\, with higher cell hunger rates
  leads to longer incubation periods\, while scaffold elastic compliance sl
 ightly affects overall growth. Furthermore\, decreasing the scaffold elast
 ic compliance while maintaining a constant nutrient consumption rate resul
 ts in an optimal funnel-shaped channel geometry\, where the upper part of 
 the channel is larger than the downstream\, promoting enhanced tissue inte
 gration and functionality.\n\nHost: Nathan Gaby (ngaby1@gsu.edu)
GEO:33.754711;-84.388068
LOCATION:25 Park Place Building (SunTrust Tower)\, 1441
SUMMARY:Applied and Computational Math Seminar: Optimizing Cell Proliferati
 on in Tissue Engineering: Interplay of Nutrient Dynamics\, Scaffold Elasti
 city\, and Cell Hunger Rate in Scaffold Channels
URL;VALUE=URI:https://calendar.gsu.edu/event/applied-and-computational-math
 -seminar-optimizing-cell-proliferation-in-tissue-engineering-interplay-of-
 nutrient-dynamics-scaffold-elasticity-and-cell-hunger-rate-in-scaffold-cha
 nnels
CATEGORIES:Lecture
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